The promising role of antibody drug conjugate in cancer therapy: Combining targeting ability with cytotoxicity effectively.
Wen-Qian LiHan-Fei GuoLing-Yu LiYong-Fei ZhangJiu-Wei CuiPublished in: Cancer medicine (2021)
ADC has changed traditional treatment patterns for cancer patients, which enable the same treatment for pancreatic cancer patients and promote individualized precision treatment. Further exploration of indications could focus on early-stage cancer patients and combined therapy settings. Besides, the mechanisms of drug resistance, manufacturing techniques, optimized treatment regimens, and appropriate patient selection remain the major topics.