Improved Pharmacokinetics with BAY 81-8973 Versus Antihemophilic Factor (Recombinant) Plasma/Albumin-Free Method: A Randomized Pharmacokinetic Study in Patients with Severe Hemophilia A.

Anita ShahAlexander SolmsDirk GarmannYvonne KatterleVerzhiniya AvramovaStanislav SimeonovToshko Lissitchkov

Published in: Clinical pharmacokinetics (2018)

BAY 81-8973 showed a superior PK profile versus rAHF-PFM. The same FVIII trough threshold level could be achieved with lower doses of BAY 81-8973 versus rAHF-PFM. ClinicalTrials.gov: NCT02483208.

Keyphrases

early onset
water quality