Memory Enhancing and Neurogenesis Activity of Honey Bee Venom in the Symptoms of Amnesia: Using Rats with Amnesia-like Alzheimer's Disease as a Model.

Khaled M KhleifatNafe M Al-TawarahMohammad A Al-KafaweenWe'am Al-KsasbehHaitham QarallehMoath AlqaralehKhawla D Al-HamaidehYousef M Al-SarairehAhmad Z Al-SarayrehYaseen T Al-QaisiAbu Bakar Mohd Hilmi

Published in: Current Alzheimer research (2023)

This study revealed that injecting BV enhances and increases the performance of both WM and LTM. Conclusively, BV has a potential nootropic and therapeutic activity that enhances hippocampal growth and plasticity, which in turn improves WM and LTM. Given that this research was conducted using scopolamine-induced amnesia-like AD in rats, it suggests that BV has a potential therapeutic activity for the enhancement of memory in AD patients in a dose-dependent manner but further investigations are needed.

Keyphrases

lps induced
lipopolysaccharide induced
end stage renal disease
working memory
newly diagnosed
chronic kidney disease
inflammatory response
high glucose
endothelial cells
cognitive decline
brain injury
patient reported outcomes
blood brain barrier
subarachnoid hemorrhage