Comparative risk of Clostridium difficile infection between proton pump inhibitors and histamine-2 receptor antagonists: A 15-year hospital cohort study using a common data model.
Seung In SeoSeng Chan YouChan Hyuk ParkTae Joon KimYou Sang KoYerim KimJong Jin YooJinseob KimWoon Geon ShinPublished in: Journal of gastroenterology and hepatology (2020)
In long-term hospital cohort, outpatient-based PPIs were associated with greater risk of CDI than H2RAs. It is necessary to be cautioned about complication of CDI in patients taking long-term PPI therapy.