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Molecular markers for the classification of cytologically indeterminate thyroid nodules.

M MuzzaC ColomboG PogliaghiO KarapanouLaura Fugazzola
Published in: Journal of endocrinological investigation (2019)
In the present review, the most recent available versions of commercial molecular tests and of custom, non-commercial panels are described. Their characteristics and accuracy in the differential diagnosis of indeterminate nodules, namely Bethesda classes III (Atypical follicular lesion of undetermined significance, AUS/FLUS) and IV (Suspicious for follicular neoplasm, FN/SFN) are fully analyzed and discussed.
Keyphrases
  • fine needle aspiration
  • ultrasound guided
  • machine learning
  • deep learning
  • single molecule
  • low grade