Eosinophil Depletion as a Potential Therapeutic Strategy in Acute and Chronic Intestinal Inflammation Based on a Dextran Sulfate Sodium Colitis Model.

Inge JacobsSara DeleuJonathan CremerGert De HertoghSéverine VermeireChristine BreynaertTim VanuytselBram Verstockt

Published in: Inflammatory bowel diseases (2024)

Eosinophil depletion prevents and decreases intestinal inflammation in a preclinical dextran sulfate sodium model without affecting fibrosis. These results pave the way for exploring eosinophil depletion as a novel treatment modality in addressing intestinal inflammation.

Keyphrases

oxidative stress
liver failure
drug induced
stem cells
intensive care unit
mesenchymal stem cells
hepatitis b virus
combination therapy
acute respiratory distress syndrome