Allyl isothiocyanate attenuates LED light-induced retinal damage in rats: exploration for the potential molecular mechanisms.

Cemal Orhan Hasan Gencoglu Mehmet Tuzcu Nurhan Şahin Ibrahim Hanifi ÖzercanAbhijeet Ashok MordeMuralidhara PadigaruKazım Şahin

Published in: Cutaneous and ocular toxicology (2021)

In conclusion, four weeks of AITC administration to the rats showed specific protective effects against two days of intense LED light-induced retinal damage; through antiinflammatory, antioxidant, anti-apoptotic, and modulating mitochondrial metabolic pathways.

Keyphrases

oxidative stress
optical coherence tomography
diabetic retinopathy
anti inflammatory
cell death
optic nerve
signaling pathway
risk assessment
climate change