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Iron concentrations in neurons and glial cells with estimates on ferritin concentrations.

Anja ReinertMarkus MorawskiJohannes SeegerThomas ArendtTilo Reinert
Published in: BMC neuroscience (2019)
Glial cells are the most iron-rich cells in the brain. Imbalances in iron homeostasis that lead to neurodegeneration may not only be originate from neurons but also from glial cells. It is feasible to estimate the ferritin concentration based on measured iron concentrations and a reasonable assumptions on iron load in the brain.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • iron deficiency
  • endoplasmic reticulum stress
  • signaling pathway
  • cell death
  • cell proliferation
  • multiple sclerosis
  • functional connectivity
  • brain injury
  • cerebral ischemia