Soluble PD-L1 as a diagnostic and prognostic biomarker in resectable gastric cancer patients.
Mihaela Chivu-EconomescuVlad HerleaSimona DimaAndrei SoropCatalin PechianuAlexandru ProcopShuji KitaharaLaura NeculaLilia MateiDenisa DraguAna-Iulia NeaguCoralia BleotuCarmen C DiaconuIrinel PopescuDan G DudaPublished in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2023)
sPD-L1 was readily measurable in GC patients, and its level was associated with GC tissue PD-L1 expression, greater inflammatory cell infiltration, disease progression, and survival. Thus, sPD-L1 may be a useful minimally invasive diagnostic and prognostic biomarker in GC patients.