Levothyroxine for a high-normal TSH in unexplained infertility.
Francesca GalbiatiTahereh Orouji JokarLars M HowellRunjia LiLindsay T FourmanHang LeeJong-Hyeon JeongPouneh K FazeliPublished in: Clinical endocrinology (2023)
Women with unexplained infertility and high-normal TSH levels treated with levothyroxine had a higher rate of conception but lower live birth rate compared to untreated women, with the limitation of a small sample size. These findings assert the need for prospective, randomized studies to determine whether treatment with levothyroxine in women with unexplained infertility and high-normal TSH is beneficial.