The critical role of macrophages in the pathogenesis of hidradenitis suppurativa.
Ahmed ShahRaed AlhusayenSaeid Amini-NikPublished in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2017)
The overexpression of pro-inflammatory cytokines and subsequent efficacy of anti-cytokine biologic therapies highlights the importance of managing macrophage dysfunction. Future therapies should target key molecular drivers of macrophage dysfunction such as TLR2 and NLRP3 overexpression.