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The effect of Vortioxetine on the NLRP3 pathway and microglial activity in the prefrontal cortex in an experimental model of depression.

Gülin Ozdamar UnalDuygu Kumbul DoğuçKuyaş Hekimler ÖztürkGamze ErkılınçFeyza DönmezEltaf Doğan KıranRamazan Oğuz Yuceer
Published in: Immunopharmacology and immunotoxicology (2024)
According to these results, it may be considered that NLRP3 inflammasome-associated neuroinflammatory response and microglial activation may play a role in the etiopathogenesis of ELS.
Keyphrases
  • nlrp inflammasome
  • prefrontal cortex
  • inflammatory response
  • lipopolysaccharide induced
  • lps induced
  • neuropathic pain
  • major depressive disorder
  • depressive symptoms
  • sleep quality
  • physical activity