Association of Small Fiber Function with Microvascular Perfusion of Peripheral Nerves in Patients with Type 2 Diabetes : Study using Quantitative Sensory Testing and Magnetic Resonance Neurography.
Christoph M MooshageLukas SchimpfleZoltan KenderDimitrios TsilingirisTaraneh Aziz-SafaieAnja HohmannJulia SzendroediPeter NawrothVolker SturmSabine HeilandMartin BendszusStefan KopfFelix T KurzJohann Malte Enno JendePublished in: Clinical neuroradiology (2023)
The findings suggest that parameters of peripheral nerve microcirculation are related to different symptoms in SFN: A reduced capillary permeability may result in a loss of function related to insufficient nutritional supply, whereas increased capillary permeability may be accompanied by painful symptoms related to a gain of function.