Cytoplasmic FMR1-interacting protein 2 allelic variation influences free-choice ethanol drinking, but not binge-like drinking or wheel-running activity, in C57BL/6J and C57BL/6NJ mice.

Matthew C HartmannWalter D McCulleySarah E HolbrookMegan M HaneyCaitlin G SmithVivek KumarAlan M Rosenwasser

Published in: Alcohol (Hanover, York County, Pa.) (2023)

These results contribute to the characterization of behavior-genetic differences between B6 substrains, support previous work indicating that free-choice and binge-like ethanol drinking are dependent on partially distinct genetic networks, and identify a novel phenotypic difference between B6 substrains in wheel-running activity.

Keyphrases

alcohol consumption
genome wide
high intensity
copy number
high fat diet induced
gene expression
amino acid
anorexia nervosa