Characteristics of lung cancer among patients with idiopathic pulmonary fibrosis and interstitial lung disease - analysis of institutional and population data.
Joo Heung YoonMehdi NouraieXiaoping ChenRichard H ZouJacobo SellaresKristen L VeraldiJared ChiarchiaroKathleen LindellDavid O WilsonNaftali KaminskiTimothy BurnsHumberto Trejo BittarSamuel YousemKevin GibsonDaniel J KassPublished in: Respiratory research (2018)
Lung cancer is approximately 3.34 times more frequently diagnosed in IPF patients compared to general population, and associated with worse prognosis compared with IPF without lung cancer, with squamous cell carcinoma and lower lobe predilection. The causality between non-smoking IPF patients and lung cancer is to be determined.