The central pattern of weakness of ALS: Morphological correlates in whole-body muscle MRI.

Nathalie WimmerHans-Peter MüllerPatrick MetzeVolker RascheAlbert C LudolphJan Kassubek

Published in: Annals of clinical and translational neurology (2024)

In conclusion, whole-body MRI-based muscle analysis provided additional evidence for a characteristic pattern of pareses in ALS. This technical approach (parameterization and quantification of muscle alterations from MRI) to patients with ALS could pave the way for the future establishment of a diagnostic algorithm of muscle MRI for ALS and may serve as a biomarker.

Keyphrases

contrast enhanced
magnetic resonance imaging
skeletal muscle
amyotrophic lateral sclerosis
diffusion weighted imaging
machine learning
magnetic resonance
deep learning