Quercetin decreases the antinociceptive effect of diclofenac in an arthritic gout-pain model in rats.

Rosa Ventura-Martinez Myrna Deciga-CamposAraceli Bustamante-MarquinaGuadalupe Esther Ángeles-LópezJosé Aviles-HerreraMaria Eva González-TrujanoGabriel Navarrete-Vázquez

Published in: The Journal of pharmacy and pharmacology (2022)

All these data demonstrated that the simultaneous administration of QUER + DIC produces an unfavorable interaction on the antinociceptive effect of DIC. Therefore, this combination might not be recommendable to relieve arthritic gout-pain.

Keyphrases

chronic pain
pain management
uric acid
neuropathic pain
anti inflammatory
electronic health record
big data
spinal cord
machine learning