Hemodynamic Bedside Monitoring Instrument with Pressure and Optical Sensors: Validation and Modality Comparison.
Matti KaistiTuukka PanulaJukka-Pekka SirkiäMikko PänkääläTero KoivistoTeemu NiiranenIlkka KantolaPublished in: Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Results from two independent clinical validation studies for measuring hemodynamics at the patient's bedside using a compact finger probe are reported. Technology comprises a barometric pressure sensor, and in one implementation, additionally, an optical sensor for photoplethysmography (PPG) is developed, which can be used to measure blood pressure and analyze rhythm, including the continuous detection of atrial fibrillation. The capabilities of the technology are shown in several form factors, including a miniaturized version resembling a common pulse oximeter to which the technology could be integrated in. Several main results are presented: i) the miniature finger probe meets the accuracy requirements of non-invasive blood pressure instrument validation standard, ii) atrial fibrillation can be detected during the blood pressure measurement and in a continuous recording, iii) a unique comparison between optical and pressure sensing mechanisms is provided, which shows that the origin of both modalities can be explained using a pressure-volume model and that recordings are close to identical between the sensors. The benefits and limitations of both modalities in hemodynamic monitoring are further discussed.
Keyphrases
- blood pressure
- atrial fibrillation
- heart rate
- hypertensive patients
- high resolution
- high speed
- heart failure
- left atrial
- oral anticoagulants
- low cost
- healthcare
- left atrial appendage
- primary care
- catheter ablation
- living cells
- direct oral anticoagulants
- type diabetes
- blood glucose
- metabolic syndrome
- patient reported outcomes
- quality improvement
- insulin resistance
- adipose tissue
- label free
- loop mediated isothermal amplification
- clinical evaluation