Patch-seq shows the heterogeneity of pancreatic islet cells.
Shun-Ichiro AsaharaPublished in: Journal of diabetes investigation (2021)
In 2016, Patch-seq was established to analyze electrophysiology, gene expression and morphology in neuronal cells. Recently, Camunas-Soler et al. used Patch-seq to analyze the functions and gene expression profiles of individual cells in pancreatic islets. I believe this analysis is expected to contribute to the complete characterization of pancreatic islets in diabetes patients.
Keyphrases
- induced apoptosis
- gene expression
- cell cycle arrest
- single cell
- genome wide
- end stage renal disease
- rna seq
- type diabetes
- dna methylation
- chronic kidney disease
- cardiovascular disease
- cell death
- endoplasmic reticulum stress
- newly diagnosed
- metabolic syndrome
- insulin resistance
- skeletal muscle
- cerebral ischemia
- patient reported
- patient reported outcomes