Associations between plasma nucleoside reverse transcriptase inhibitors concentrations and cognitive function in people with HIV.
Davide De FrancescoXinzhu WangLaura DickinsonJonathan UnderwoodEmmanouil BagkerisDaphne S BabalisPatrick W G MallonFrank A PostJaime H VeraMemory SachikonyeIan WilliamsSaye KhooCaroline A SabinAlan WinstonMarta Boffitonull nullPublished in: PloS one (2021)
Whilst we found no evidence of either detrimental or beneficial effects of ABC, FTC and TFV plasma exposure on cognitive function of PWH, higher plasma 3TC exposures were generally associated with better cognitive performance although higher peak concentrations were associated with poorer performance.