Metabolomic signature of the seminal plasma in men with severe oligoasthenospermia.

Magalie BoguenetCinzia BoccaPierre-Emmanuel BouetOrianne SerriStéphanie ChupinLydie TessierOdile BlanchetHady El HachemJuan Manuel Chao de la BarcaPascal ReynierPascale May-Panloup

Published in: Andrology (2020)

We provide a global overview of the metabolic defects contributing to the structural and functional alteration of spermatozoa in severe oligoasthenospermia. These findings offer new insights into the pathophysiology of male factor infertility that could help to develop future specific treatments.

Keyphrases

early onset
drug induced
type diabetes
metabolic syndrome
insulin resistance