miRNA-regulated transcription associated with mouse strains predisposed to hypnotic effects of ethanol.

Brian E VestalP RussellR A RadcliffeL BemisL M SabaK Kechris

Published in: Brain and behavior (2018)

Our results suggest a novel role of miRNA-mediated regulation of an inhibitor of CAMK2 and its downstream targets including the GABAA and NMDA receptors, which have been previously implicated to have a role in ethanol-induced sedation and sensitivity.

Keyphrases

transcription factor
high glucose
escherichia coli
diabetic rats
mechanical ventilation
oxidative stress
endothelial cells
intensive care unit
acute respiratory distress syndrome
extracorporeal membrane oxygenation
stress induced