Failure of preventive treatments in migraine: an observational retrospective study in a tertiary headache center.
Marianna DelussiEleonora VecchioGiuseppe LibroSilvia QuitadamoMarina de TommasoPublished in: BMC neurology (2020)
The mild effect of preventive drugs on migraine features and even the number of patients who were lost to follow-up or dropped out because of adverse events confirm that in severe and chronic patients, the first line of prevention can only delay a more focused therapeutic approach.