Selective binding of c-MYC G-quadruplex caged in a dsDNA by a hemopeptide.

Leen MassalhaAdiel Richter LevinNurit Adiram-FilibaEyal Golub

Published in: Chemical communications (Cambridge, England) (2024)

The microperoxidase-11 hemopeptide exhibits configuration-dependent selectivity for guanine-quadruplexes by specifically uncaging c-MYC guanine-quadruplexes from a duplex DNA.

Keyphrases

circulating tumor
cell free
single molecule
dna binding
binding protein
nucleic acid