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New distance measure for comparing protein using cellular automata image.

Luryane F SouzaHernane B de B PereiraTarcísio M Rocha FilhoBruna A S MachadoMarcelo A Moret
Published in: PloS one (2023)
One of the first steps in protein sequence analysis is comparing sequences to look for similarities. We propose an information theoretical distance to compare cellular automata representing protein sequences, and determine similarities. Our approach relies in a stationary Hamming distance for the evolution of the automata according to a properly chosen rule, and to build a pairwise similarity matrix and determine common ancestors among different species in a simpler and less computationally demanding computer codes when compared to other methods.
Keyphrases
  • amino acid
  • protein protein
  • deep learning
  • binding protein
  • machine learning
  • data analysis