Arterial stiffness is associated with oxidative stress and endothelial activation among persons with treated HIV in Zambia.
Theresa ChikopelaFastone M GomaLonga KalubaWilbroad MutaleChris GuureDouglas Corbett HeimburgerJohn R KoethePublished in: Southern African journal of HIV medicine (2021)
PLWH in sub-Saharan Africa had significantly greater oxidative stress and endothelial activation compared to HIV-negative individuals. These factors may contribute to increased arterial stiffness and higher CVD prevalence in this population.
Keyphrases
- oxidative stress
- antiretroviral therapy
- hiv positive
- hiv infected
- hiv testing
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- blood pressure
- men who have sex with men
- endothelial cells
- dna damage
- diabetic rats
- ischemia reperfusion injury
- risk factors
- induced apoptosis
- south africa
- newly diagnosed
- heat shock
- endoplasmic reticulum stress
- heat stress