The mitochondrial TSPO ligand Atriol mitigates metabolic-associated steatohepatitis by downregulating CXCL1.

Yuchang LiLiting ChenChantal SottasMahima Chandrakant RaulNrupa Dinesh PatelJanaki Ramulu BijjaS Kaleem AhmedAudrey Kapelanski-LamoureuxAnthoula LazarisPeter MetrakosAlexander ZambidisShefali ChopraMeng LiGo SugaharaTakeshi SaitoVassilios Papadopoulos

Published in: Metabolism: clinical and experimental (2024)

Atriol ameliorates MASH both in vitro and in vivo, demonstrating its potential therapeutic benefits in managing MASH.

Keyphrases

oxidative stress
pet imaging
mouse model
radiation induced
radiation therapy
pet ct