Association between higher intermuscular adipose tissue and decreased renal function in patients with systemic lupus erythematosus mediated by insulin resistance.

Bowen WangLiping ZuoJinlei FanYu JiLei XuMin XuYueming AnYuting ZhangGuanming JiDe-Xin Yu

Published in: Insights into imaging (2024)

High intramuscular adipose tissue (IMAT) area was associated with decreased renal function in systemic lupus erythematosus (SLE) patients. Insulin resistance mediated the association between IMAT area and eGFR. IMAT area was associated with chronicity index in lupus nephritis patients.

Keyphrases

adipose tissue
insulin resistance
end stage renal disease
chronic kidney disease
ejection fraction
high fat diet
small cell lung cancer
type diabetes
metabolic syndrome
skeletal muscle
polycystic ovary syndrome
patient reported outcomes
epidermal growth factor receptor
weight loss
disease activity