Determinants of Drug-Induced Hepatotoxicity Among Patients with Human Immunodeficiency Virus Taking a High Dose of Rifapentine Plus Isoniazid Drugs at the All Africa Leprosy Tuberculosis Rehabilitation and Training Center in Addis Ababa, Ethiopia.
Leuel Lisanwork ArageHaji Aman DeybassoDelelegn Yilma GebremichaelBinyam Gintamo NuramoZelalem Negash MekuriaPublished in: HIV/AIDS (Auckland, N.Z.) (2021)
The prevalence of anti-TB drug-induced hepatotoxicity was higher compared to standard references. BMI<18 kg/m2, low CD4 count, and comorbid illness were positively associated with anti-tuberculosis drug-induced hepatotoxicity among patients with HIV.
Keyphrases
- drug induced
- human immunodeficiency virus
- mycobacterium tuberculosis
- liver injury
- antiretroviral therapy
- hiv aids
- hepatitis c virus
- high dose
- hiv infected
- adverse drug
- hiv positive
- pulmonary tuberculosis
- body mass index
- risk factors
- hiv testing
- weight gain
- physical activity
- emergency department
- nk cells
- weight loss
- electronic health record