GIT1 regulates angiogenic factor secretion in bone marrow mesenchymal stem cells via NF-κB/Notch signalling to promote angiogenesis.

Linwei LiPengyu TangZheng ZhouQian WangTao XuShujie ZhaoYifan HuangFanqi KongWei LiuLin ChengZhimin ZhouXuan ZhaoChangjiang GuYongjun LuoGaojian TaoDingfei QianJian ChenJin FanGuoyong Yin

Published in: Cell proliferation (2019)

These data revealed a positive role for GIT1 by modulating the Notch/NF-κB signals which promoting paracrine of BMSCs to enhance angiogenesis and fracture healing.

Keyphrases

signaling pathway
endothelial cells
lps induced
vascular endothelial growth factor
pi k akt
cell proliferation
nuclear factor
oxidative stress
electronic health record
single cell
inflammatory response
big data
machine learning
toll like receptor
data analysis