Inhibiting interferon-γ induced cancer intrinsic TNFRSF14 elevation restrains the malignant progression of glioblastoma.

Yunhe HanCunyi ZouTianqi LiuWen ChengPeng ChengAn-Hua Wu

Published in: Journal of experimental & clinical cancer research : CR (2024)

Our findings highlight a malignant TNFRSF14/FAK axis as a potential target to blunt cancer-intrinsic resistance to ICB treatment, which may help improve the therapeutic efficiency of immunotherapy in malignancies.

Keyphrases

papillary thyroid
signaling pathway
high glucose
lymph node metastasis
dendritic cells
squamous cell carcinoma
young adults
childhood cancer
oxidative stress
immune response
risk assessment
human health
stress induced