Cardiac Magnetic Resonance Imaging and Clinical Follow-up in Antimalarial-induced Cardiomyopathy in Patients With Systemic Lupus Erythematosus.
Tamar ShalmonPaaladinesh ThavendiranathanPaula HarveyShadi AkhtariKostantinos TseliosDafna D GladmanKate HannemanPublished in: Journal of thoracic imaging (2023)
Antimalarial-induced cardiomyopathy is under-recognized in clinical practice and there is limited data on the evolution of cardiac imaging abnormalities after cessation of anti-malarial therapy. In this case series of 9 patients with antimalarial-induced cardiomyopathy, follow-up cardiac magnetic resonance imaging demonstrated interval increase in late gadolinium enhancement extent in 89% of patients and interval decrease in left ventricular ejection fraction in all, despite cessation of anti-malarial therapy. Progression of cardiac abnormalities despite cessation of therapy underscores the important role of imaging in the early recognition of antimalarial-related treatment changes.
Keyphrases
- ejection fraction
- left ventricular
- magnetic resonance imaging
- plasmodium falciparum
- aortic stenosis
- heart failure
- high glucose
- high resolution
- diabetic rats
- drug induced
- end stage renal disease
- computed tomography
- acute myocardial infarction
- contrast enhanced
- stem cells
- prognostic factors
- endothelial cells
- mitral valve
- electronic health record
- left atrial
- photodynamic therapy
- mesenchymal stem cells
- patient reported