Tumour response in non-small-cell lung cancer patients treated with chemoradiotherapy - Can spectral CT predict recurrence?

Fehrenbach Uli Felix W FeldhausJohannes KahnGeorg BöningMartin H MaurerDiane RenzNikolaj FrostFlorian Streitparth

Published in: Journal of medical imaging and radiation oncology (2019)

Spectral CT-derived iodine content of NSCLC following CRT may help in predicting recurrence. Hotspot analysis and iodine heterogeneity allow the identification of residual vascularisation as an indicator of vital tumour tissue, indicating that IC might be a suitable imaging biomarker for predicting tumour progression. Iodine content and spectral slope analysis might also help in identifying metastatic lymph nodes.

Keyphrases

dual energy
computed tomography
image quality
lymph node
small cell lung cancer
optical coherence tomography
contrast enhanced
heart failure
mass spectrometry
rectal cancer
free survival
radiation therapy
early stage
photodynamic therapy
fluorescence imaging
cardiac resynchronization therapy