Diagnostic salivary biomarkers in oral cancer and oral potentially malignant disorders and their relationships to risk factors - A systematic review.
Piyarathne NadishaR M S G K RasnayakeRandilini AngammanaPushpika ChandrasekeraSamantha RamachandraManjula Manoji WeerasekeraSurangi YasawardeneRasha Abu-EidJ A P JayasingheEkta GuptaPublished in: Expert review of molecular diagnostics (2021)
A salivary biomarker panel including Interleukin (IL) 1β, IL6, and IL8 was selected for OSCC and OPMD. Reported relationships between salivary biomarkers and risk factors are discussed and research gaps are highlighted. Future research should be directed to assess potential salivary biomarkers and their relationships to risk factors in order to understand the biomarker's role in disease initiation.