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LooplessFluxSampler: an efficient toolbox for sampling the loopless flux solution space of metabolic models.

Pedro A SaaSebastian ZapararteChristopher C DrovandiLars K Nielsen
Published in: BMC bioinformatics (2024)
LooplessFluxSampler enables scalable statistical inference of the loopless mass-balanced solution space of large metabolic models. Grounded in a theoretically sound framework, this toolbox provides not only efficient but also reliable results for exploring the properties of the almost surely non-convex loopless flux space. Finally, LooplessFluxSampler includes a Markov Chain diagnostics suite for assessing the quality of the final sample and the performance of the algorithm.
Keyphrases
  • machine learning
  • deep learning