Effects of Opioid Withdrawal on Psychobiology in People Living with HIV.

Igor GrantEvgeny KrupitskyMarina VetrovaAnya UmlaufRobert K HeatonRichard L HaugerOlga ToussovaDonald R FranklinScott L LetendreGeorge WoodyElena BlokhinaDmitriy A Lioznov Edwin E Zvartau

Published in: Viruses (2024)

Worsening of cognition and measures of mood disturbance during withdrawal were associated with activation of the HPA axis and some measures of inflammation. Whether repeated episodes of opioid withdrawal have a cumulative impact on long-term HIV outcomes and neurocognition is a topic for further investigation.

Keyphrases

chronic pain
pain management
antiretroviral therapy
oxidative stress
hiv positive
hiv infected
human immunodeficiency virus
bipolar disorder
hiv testing
mild cognitive impairment
hiv aids
sleep quality
white matter
metabolic syndrome
south africa
insulin resistance
depressive symptoms