Epileptogenic focal lesions in Dravet syndrome: A warning to investigators.
Rita Monteiro VenturaÁlvaro Beltrán-CorbelliniRafael ToledanoIrene Sánchez-Miranda RománIrene García-MoralesAntonio Gil-NagelPublished in: Epileptic disorders : international epilepsy journal with videotape (2023)
When an individual with an established diagnosis of genetic epilepsy and a focal lesion on MRI is undergoing preoperative evaluation, it is crucial to conduct a comprehensive analysis to understand the relevance of the focal finding for the patient's phenotype and thus anticipate potential surgical outcomes. In instances where epilepsy in DS patients is influenced by a specific focal structural lesion, resective surgery should be carefully considered after precise pharmacological treatment, acknowledging the persistent influence of an SCN1A variant on expected outcomes.
Keyphrases
- end stage renal disease
- case report
- ejection fraction
- newly diagnosed
- minimally invasive
- chronic kidney disease
- magnetic resonance imaging
- peritoneal dialysis
- type diabetes
- patients undergoing
- coronary artery bypass
- copy number
- dna methylation
- contrast enhanced
- atrial fibrillation
- climate change
- coronary artery disease
- insulin resistance
- diffusion weighted imaging
- replacement therapy
- temporal lobe epilepsy
- clinical evaluation