Integrase strand transfer inhibitor (INSTI) related changes in BMI and risk of diabetes: a prospective study from the RESPOND cohort consortium.

Dhanushi RupasingheLoveleen Bansi-MatharuMatthew LawRobert ZangerleAndri RauchPhilip E TarrLauren GreenbergBastian NeesgaardNadine JaschinskiStéphane De WitFerdinand WitAntonella d'Arminio MonforteEric FontasAntonella CastagnaMelanie StecherVanessa BrandesEric FlorenceJosip BegovacCristina MussiniAnders SönnerborgAkaki AbutidzeAna GrohVani VannappagariCal CohenLital YoungSean HoseinLene RyomKathy Petoumenos

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2024)

In RESPOND, compared with non-INSTIs, current use of INSTIs was associated with an increased DM risk, which partially attenuated when adjusted for BMI changes and other variables.

Keyphrases

body mass index
glycemic control
type diabetes
weight gain
cardiovascular disease
adipose tissue
skeletal muscle
insulin resistance
electron transfer