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Dysregulated follicular regulatory T cells and antibody responses exacerbate experimental autoimmune encephalomyelitis.

Lin LuoXianzhen HuMichael L DixonBrandon J PopeJonathan D LeavenworthChander RamanWilliam R MeadorJianmei Wu Leavenworth
Published in: Journal of neuroinflammation (2021)
Blimp1 is essential for the maintenance of TFR cells and Ab responses in EAE. Dysregulated TFR cells and Ab responses promote CNS autoimmunity.
Keyphrases
  • regulatory t cells
  • induced apoptosis
  • cell cycle arrest
  • dendritic cells
  • endoplasmic reticulum stress
  • signaling pathway
  • oxidative stress
  • immune response