Protection conferred by COVID-19 vaccination, prior SARS-CoV-2 infection, or hybrid immunity against Omicron-associated severe outcomes among community-dwelling adults.

Nelson LeeLena NguyenPeter C AustinKevin A BrownRamandip GrewalSarah E Wilson Sharifa NasreenJonathan GubbayKevin L SchwartzMina TadrousKumanan WilsonSarah E WilsonJeffrey C Kwong

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)

Protection from COVID-19 vaccines and/or prior SARS-CoV-2 infections against severe outcomes is reduced when immune-evasive variants/subvariants emerge and may also wane over time. Our findings support a variant-adapted booster vaccination strategy with periodic review.

Keyphrases

sars cov
respiratory syndrome coronavirus
community dwelling
coronavirus disease
early onset
drug induced
metabolic syndrome
type diabetes
adipose tissue
weight loss
insulin resistance