Verification of the effects of calcium channel blockers on the immune microenvironment of breast cancer.

Koji TakadaShinichiro KashiwagiYuka AsanoWataru GotoKatsuyuki TakahashiHisakazu FujitaTsutomu TakashimaShuhei TomitaKosei HirakawaMasaichi Ohira

Published in: BMC cancer (2019)

In patients with TNBC undergoing treatment for hypertension with CCBs, TILs in the needle biopsy specimens before treatment were significantly lower, and the response rate of POC was not sufficient. Thus, the immunosuppressive effects of CCBs may also affect the immune microenvironment.

Keyphrases

stem cells
blood pressure
ultrasound guided
fine needle aspiration
young adults
combination therapy
angiotensin converting enzyme
angiotensin ii
replacement therapy