Cathine and cathinone disposition kinetics and neurotransmitter profile in several organs of rats exposed to a single dose of Catha edulis (Vahl) Forssk. ex Endl. extract.
Ahmad M AlamirMohammed A JeraibyHesham M KorashyEmad Sayed ShaheenMohammad A AttafiMagbool E OraibyAhmed M HakamiMohammed Y AlbeishyIbrahim A KhardaliIsmail A JuraybiAbeer A AlobaidaIbraheem M AttafiPublished in: Drug metabolism and personalized therapy (2023)
in the heart tissues but not in the brain. In addition, neurotransmitters such as adrenaline, dopamine, norepinephrine, and serotonin were differentially detected in all tested samples in a organ-specific fashion. More study is needed to identify cathine and cathinone's effects on neurotransmitter profiles. Nevertheless, these findings provided a further basis for experimental, clinical, and forensic investigations.