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Laboratory evaluation of twelve portable devices for medicine quality screening.

Stephen C ZambrzyckiCéline CailletSerena VickersMarcos BouzaDavid V DonndelingerLaura C GebenMatthew C BernierPaul N NewtonFacundo M Fernández
Published in: PLoS neglected tropical diseases (2021)
The twelve devices evaluated could detect medicines with the wrong or none of the APIs, consistent with falsified medicines, with high accuracy. However, API quantitation to detect formulations similar to those commonly found in substandards proved more difficult, requiring further technological innovation.
Keyphrases
  • ms ms
  • mass spectrometry
  • liquid chromatography tandem mass spectrometry
  • liquid chromatography
  • high performance liquid chromatography
  • simultaneous determination