Epidermal Growth Factor Receptor T790M Mutation Testing in Non-Small Cell Lung Cancer: An International Collaborative Study to Assess Molecular EGFR T790M Testing in Liquid Biopsy.
Martin FilipitsVerena KainzViktor SebekHerwig Zachnull On Behalf Of The Liquid Biopsy Collaborative Study GroupPublished in: Cancers (2023)
If a negative result was obtained from methods with lower sensitivity (e.g., Cobas), repeated liquid biopsy testing and/or tissue biopsy analysis should be performed whenever possible, to identify T790M-positive patients to allow them to receive the optimal second-line treatment with a third-generation EGFR TKI.
Keyphrases
- epidermal growth factor receptor
- tyrosine kinase
- advanced non small cell lung cancer
- ultrasound guided
- fine needle aspiration
- small cell lung cancer
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- ionic liquid
- prognostic factors
- patient reported outcomes
- smoking cessation
- replacement therapy