Proposing anti-counterfeiting pharmacopoeia quality markers for Shenlingbaizhu granule based on UHPLC-Q-orbitrap-MS identification.

Jingyuan ZengXican LiRongxin CaiBan ChenChunhou LiQingzhong HuYue Sun

Published in: Phytochemical analysis : PCA (2023)

The study recommends glycyrrhizic acid, ginsenoside Re, ginsenoside Rb1, and diosgenin as four anti-counterfeiting Q-markers for the pharmacopoeia. The anti-counterfeiting Q-markers can be detected using conventional HPLC. The observation of 17 unexpected compounds updates our knowledge regarding the bioactives of Shenlingbaizhu granule.

Keyphrases

ms ms
mass spectrometry
simultaneous determination
healthcare
tandem mass spectrometry
multiple sclerosis
ultra high performance liquid chromatography
high resolution mass spectrometry
solid phase extraction