Risk factors for liver-related mortality of patients with hepatitis C virus after sustained virologic response to direct-acting antiviral agents.
Nobuhiro HattoriHiroki IkedaTsunamasa WatanabeYosuke SattaTakuya EhiraTatsuya SuzukiHirofumi KiyokawaKazunari NakaharaHideaki TakahashiKotaro MatsunagaNobuyuki MatsumotoHiroshi YasudaMichihiro SuzukiFumio ItohKeisuke TateishiPublished in: JGH open : an open access journal of gastroenterology and hepatology (2022)
Our findings suggest that DM and a history of HCC are risk factors for liver-related mortality of HCV patients cured by DAAs. These results indicate that early management of HCV and HCC surveillance of diabetic patients after SVR are important to increase the chance of survival. Further studies are needed to confirm the association of DM and HCC history with survival.
Keyphrases
- hepatitis c virus
- human immunodeficiency virus
- end stage renal disease
- cardiovascular events
- ejection fraction
- newly diagnosed
- chronic kidney disease
- risk factors
- public health
- prognostic factors
- type diabetes
- free survival
- cardiovascular disease
- adipose tissue
- hiv infected
- antiretroviral therapy
- patient reported outcomes
- glycemic control
- insulin resistance
- skeletal muscle