Induction of disease remission with one cycle of alemtuzumab in relapsing-remitting MS.
Alexandra S KocsikDavid E KleinMaryana LiedkeUlrike W KaunznerNancy M NealonSusan A GauthierTimothy VartanianJai S PerumalPublished in: Journal of neurology (2018)
Given that 96% of patients who did not relapse in the first 12 months following the initial dose of alemtuzumab remained relapse-free regardless of receiving a second course of drug, our data suggests that induction of disease remission for some patients might occur following just one dose of alemtuzumab. With further study, these data could support modification of the current therapy regimen.
Keyphrases
- multiple sclerosis
- disease activity
- end stage renal disease
- electronic health record
- chronic kidney disease
- ejection fraction
- newly diagnosed
- peritoneal dialysis
- rheumatoid arthritis
- big data
- mass spectrometry
- systemic lupus erythematosus
- prognostic factors
- ms ms
- ulcerative colitis
- stem cells
- mesenchymal stem cells
- machine learning
- data analysis
- smoking cessation