Pembrolizumab induced type 1 diabetes mellitus in a patient with metastatic melanoma and literature review on steroids as a treatment option.

Adina GreeneScott PennerJacqueline KuneshAmal AltafWilliam McGradeJiaxin Niu

Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2024)

This literature search suggests that ICI-induced T1DM cannot be reversed by steroids and that insulin must be used permanently for treatment management.

Keyphrases

high glucose
type diabetes
case report
diabetic rats
glycemic control
systematic review
drug induced
oxidative stress
adipose tissue
advanced non small cell lung cancer
weight loss
smoking cessation