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Cilofexor in Patients With Compensated Cirrhosis Due to Primary Sclerosing Cholangitis: An Open-Label Phase 1B Study.

Cynthia LevyStephen CaldwellParvez MantryVelimir LuketicCharles S LandisJonathan HuangEdward MenaRahul MaheshwariKevin RankJun XuVladislav A MalkovAndrew N BillinXiangyu LiuXiaomin LuWilliam T BarchukTimothy R WatkinsChuhan ChungRobert P MyersKris V Kowdley
Published in: Clinical and translational gastroenterology (2024)
Escalating doses of cilofexor over 12 weeks were well tolerated and improved cholestasis markers in patients with compensated cirrhosis due to primary sclerosing cholangitis (NCT04060147).
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