Comparative effectiveness of β-lactams for empirical treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a prospective cohort study.
D T P BuisThomas W van der VaartJan M PrinsJ T M van der MeerM J M BontenE SieswerdaC H van WerkhovenK C E SigaloffB L HerpersR R JansenW RozemeijerR SoetekouwG van TwillertJ VeenstraPublished in: The Journal of antimicrobial chemotherapy (2023)
In this study, we could not demonstrate a difference in duration of bacteraemia and 30 day SAB-related mortality between patients with SAB empirically treated with flucloxacillin, cefuroxime or ceftriaxone. Since sample size was limited, it is possible the study was underpowered to find a clinically relevant effect.